Brain stroke detection using deep learning pdf A preprocessing pipeline was This repository contains a Deep Learning model using Convolutional Neural Networks (CNN) for predicting strokes from CT scans. This research attempts to diagnose brain stroke from MRI using CNN and deep learning models. Machine learning algorithms are Jul 2, 2024 · Ischemic brain strokes are severe medical conditions that occur due to blockages in the brain’s blood flow, often caused by blood clots or artery blockages. Therefore, the aim of Dec 1, 2022 · A brain stroke is a life-threatening medical disorder caused by the inadequate blood supply to the brain. Stroke Cerebrovasc. Since object detection enables detailed visualizations of the impact of a stroke, it becomes a valuable tool for supporting critical decisions regarding Dec 16, 2022 · This research aims to emphasize the impact of deep learning models in brain stroke detection and lesion segmentation. Note: Perceptron Learning Algorithm (PLA), K-Center with Radial Basis Functions (RBF), Quadratic discriminant analysis (QDA), Linear Dec 8, 2022 · A brain stroke is a life-threatening medical disorder caused by the inadequate blood supply to the brain. Article; E. D. Brain stroke segmentation in magnetic resonance imaging (MRI) has become an evolving research area in the field of a BrainOK: Brain Stroke Prediction using Machine Learning Mrs. After the stroke, the damaged area of the brain will not operate normally. Stroke, a condition that ranks as the second leading cause of death worldwide, necessitates immediate treatment in order to prevent any potential damage to the brain. This project, "Brain Stroke Detection System based on CT Images using Deep Learning," leverages advanced computational techniques to enhance the accuracy and efficiency of stroke diagnosis from CT images. Several methods have been proposed to detect ischemic brain stroke automatically on CT scans using machine learning and deep learning, but they are not robust and their performance is not ready for clinical practice. 1016/j. Brain stroke detection is a critical medical process requiring prompt and accurate diagnosis to facilitate effective treatment. This paper presents a novel methodology for image reconstruction using U-Net, followed by the classification of brain stroke type Dec 31, 2024 · The contribution of this work involves is using different algorithms on a freely available dataset (from the Kaggle website), as well as methods for pre-processing the brain stroke dataset. Better methods for early detection are crucial due to the concerning increase in the number of people suffering from brain stroke. However, while doctors are analyzing each brain CT image, time is running Nov 28, 2022 · Request PDF | Brain stroke detection from computed tomography images using deep learning algorithms | This chapter, a pre-trained CNN models that can distinguish between stroke and normal on brain Jan 10, 2025 · In , the authors demonstrated a brain stroke detection system using a deep learning model. The program suggests using digital image processing technologies to detect infarcts and hemorrhages in human brain tissue. The chapter is arranged as follows: studies in brain stroke detection are detailed in Part 2. Aug 1, 2020 · Critical case detection from radiology reports is also studied, yet with different grounds. Stroke is a medical condition in which poor blood flow to the brain causes cell death and causes the brain to stop functioning properly. Sakthivel and Shiva Prasad Kaleru}, journal={2022 4th International Conference on Inventive Research in Computing Sep 1, 2023 · The accurate segmentation of brain stroke lesions in medical images are critical for early diagnosis, treatment planning, and monitoring of stroke patients. Specifically, it reviews several studies that have used techniques like random forests, artificial neural networks, support vector machines, and convolutional neural networks to accurately classify MRI scans and detect strokes with Sep 21, 2022 · DOI: 10. Download PDF. Dec 1, 2020 · The medical field also greatly benefits from the use of improving deep learning models which save time and produce accurate results. The F1 scores, precision and recall attained for the proposed model using deep learning classifiers is compared in Table 2. Dis. The data was collected from ATLAS. 105711 [ DOI ] [ PubMed ] [ Google Scholar ] Abstract—Stroke segmentation plays a crucial role in the diagnosis and treatment of stroke patients by providing spatial information about affected brain regions and the extent of damage. Oct 1, 2023 · Mariano et al. jstrokecerebrovasdis. unique approach to detect brain strokes using machine learning techniques. The World Health Organization (WHO) defines stroke as “rapidly developing clinical signs May 15, 2024 · Download Citation | Stroke detection in the brain using MRI and deep learning models | When it comes to finding solutions to issues, deep learning models are pretty much everywhere. 105711. Reddy and others published Brain Stroke Prediction Using Deep Learning: A CNN Approach | Find, read and cite all the research you need on ResearchGate Strokes damage the central nervous system and are one of the leading causes of death today. An algorithm with a seeded region growing performs classification. Arvind Choudhary Department of Computer Engineering Universal College of Engineering, Vasai, India choudharyarvind182@gmail. The pre-trained ResNetl01, VGG19, EfficientNet-B0, MobileNet-V2 and GoogleNet models were run with the same dataset and same parameters. In Section 2, we exhibit the historical development of deep learning, including convolutional neural network (CNN), recurrent neural network (RNN), autoencoder (AE), restricted Boltzmann machine (RBM), transformer, and transfer learning (TL). & Camara, J Feb 4, 2025 · Prompt identification of the type of brain stroke is a pivotal measure for medical practitioners in commencing therapeutic interventions for patients afflicted with stroke. One of the cerebrovascular health conditions, stroke has a significant impact on a person’s life and health. Deep learning techniques have emerged as a promising approach for automated brain tumor detection, leveraging the power of artificial intelligence to analyse medical images accurately and efficiently. Nov 27, 2024 · The goals of our work are manifold. The proposed methodology is to develop an automated early ischemic stroke detection system using CNN deep learning algorithm. The user will get to know about the outcome of its input data. In recent times, the spotlight has turned to machine learning methodologies for stroke detection due to their potential. 1109/ICIRCA54612. INTRODUCTION Deep learning is a type of machine learning that teaches computers to mimic human behaviour. Utilizing a pre-trained model like VGG19, transfer learning was employed to improve both accuracy and efficiency. , Koyasu S. 2 and Jun 25, 2020 · The main objective of this study is to forecast the possibility of a brain stroke occurring at an early stage using deep learning and machine learning techniques. Medical image Mar 8, 2024 · Brain-Stroke-Detection (Using Deep Learning) This project involves developing a system to detect brain strokes from medical images, such as CT or MRI scans. Using CNN and deep learning models, this study seeks to diagnose brain stroke images. Recently, deep learning technology gaining success in many domain including computer vision, image recognition Overall, deep learning has the potential to significantly improve the accuracy and speed of brain stroke detection, leading to better patient outcomes and ultimately saving lives. 8–10 November 2017; pp. There are two primary causes of brain stroke: a blocked conduit (ischemic stroke) or blood vessel spilling or blasting (hemorrhagic stroke Stroke is a medical emergency that occurs when a section of the brain’s blood supply is cut off. An automated early ischemic stroke detection system using CNN deep learning algorithm; Proceedings of the 2017 IEEE 8th International Conference on Awareness Science and Technology (iCAST); Taichung, Taiwan. Deep learning is a subfield of machine learning that aims to teach computers how to imitate human Jul 4, 2024 · We conducted a comprehensive review of 25 review papers published between 2020 and 2024 on machine learning and deep learning applications in brain stroke diagnosis, focusing on classification Nishio M. A stroke occurs when the brain’s blood supply is cut off and it ceases to function. Deep learning is a subfield of machine learning that aims to teach computers how to imitate human Nov 1, 2017 · Request PDF | On Nov 1, 2017, Chiun-Li Chin and others published An automated early ischemic stroke detection system using CNN deep learning algorithm | Find, read and cite all the research you Brain tumours pose a significant health risk, and early detection plays a crucial role in improving patient outcomes. , Lin B. Compared with several kinds of stroke, hemorrhagic and ischemic causes have a negative impact on the human central nervous system. The two models work as two-step deep learning models to classify brain normal, ischemic, and hemorrhagic conditions by model 01, while acute, subacute, Overall, deep learning has the potential to significantly improve the accuracy and speed of brain stroke detection, leading to better patient outcomes and ultimately saving lives. Medical image data is best analysed using models based on Convolutional Neural Networks (CNNs). Recently, deep learning technology gaining success in many domain including computer vision, image recognition, natural language processing and especially in medical field of radiology. By utilizing ResNet-50's deep learning capabilities, the suggested system is able to automatically evaluate medical imaging data, including CT and MRI scans, in order to spot possible stroke symptoms. Dec 1, 2020 · In recent years, deep learning algorithms have created a massive impact on addressing research challenges in different domains. Stroke symptoms belong to an emergency condition, the sooner the patient is treated, the more chance the patient recovers. It is also known as deep structured learning and is part of a larger family of machine learning approaches based on Applications of deep learning in acute ischemic stroke imaging analysis. The presented approach incorporates an improved version of VGGNet to obtain better detection accuracy. Oct 12, 2023 · In this research work, deep learning-based brain stroke detection system is presented using improved VGGNet and Experimental results validates that the Improved VGG model attained better performance for all the parameters. [3] Chutima Jalayondeja has conferred that in the prediction using demographic data and Decision Tree, Naïve Bayes, and Neural Network are the 3 models which were considered and Decision Tree May 23, 2024 · PDF | Brain stroke (BS) imposes a substantial burden on healthcare systems due to the long-term care and high expenditure. Timely diagnosis and treatment play a crucial role in reducing mortality and minimizing long-term disabilities associated with strokes. Nov 1, 2022 · A deep learning model based on a feed-forward multi-layer artificial neural network was also studied in [13] to predict stroke. 10. In order to diagnose and treat stroke, brain CT scan images Feb 27, 2025 · Takahashi N et al (2019) Computerized identification of early ischemic changes in acute stroke in noncontrast CT using deep learning. The system’s first component is a brain slice Jan 10, 2025 · Download Citation | On Jan 10, 2025, Tasnim Faruki and others published Detection of Brain Stroke Disease Using Deep Learning Techniques | Find, read and cite all the research you need on ResearchGate Jan 1, 2022 · Purpose To demonstrate automated detection and segmentation of brain metastases on multisequence MRI using a deep‐learning approach based on a fully convolution neural network (CNN). There are two types of strokes, which is ischemic and hemorrhagic. 9%, according to our findings. In their 2020 paper, "Automatic detection of brain strokes using texture analysis and deep learning," Gupta et al. This project aims to increase the speed and accuracy of stroke diagnosis using state-of-the-art deep learning techniques, allowing for prompt medical intervention. To shorten the amount of time necessary to establish the massive datasets required for training the machine learning algorithms Sep 1, 2019 · Through experimental results, it is found that deep learning models not only used in non-medical images but also give accurate result on medical image diagnosis, especially in brain stroke detection. 2020;196 doi: 10. Jul 2, 2024 · Hybrid Ensemble Deep Learning Model for Advancing Ischemic Brain Stroke Detection and Classification in Clinical Application July 2024 Journal of Imaging 10(7):160 International Research Journal of Modernization in Engineering Technology and Science) , 2024. The Sep 1, 2019 · Deep learning and CNN were suggested by Gaidhani et al. This results in approximately 5 million deaths and another 5 million individuals suffering permanent disabilities. This is achieved by discussing the state of the art approaches proposed by the have had and have not had brain strokes. Computed tomography (CT) images supply a rapid diagnosis of brain stroke. Brain Stroke is a long-term disability disease that occurs all over the world and is the leading cause of death. The model has a classification accuracy of 89. Moreover, the Brain Stroke CT Image Dataset was used for stroke classification. Stroke is a medical emergency in which poor blood flow to the brain causes cell death. 2022. Over the past few years, stroke has been among the top ten causes of death in Taiwan. Simulation analysis using a set of brain stroke data and the performance of learning algorithms are measured in terms of accuracy, sensitivity, specificity, precision, f- This research present the detection and segmentation of brain stroke using fuzzy c-means clustering and H2O deep learning algorithms. The purpose of this paper is to gather information or answer related to this paper’s research question Jan 1, 2021 · PDF | On Jan 1, 2021, Khalid Babutain and others published Deep Learning-enabled Detection of Acute Ischemic Stroke using Brain Computed Tomography Images | Find, read and cite all the research ischemic brain stroke automatically on CT scans using machine learning and deep learning, but they are not robust and their performance is not ready for clinical practice. Medical Imaging 2019: Computer-Aided Diagnosis, SPIE. First, we aim to demonstrate how Federated Learning can enhance stroke detection and prediction using Deep Learning, compared with other approaches. Two deep learning models were developed, including the 4767 CT brain images. For the offline Jun 22, 2021 · For example, Yu et al. This study proposes an accurate predictive model for identifying stroke risk factors. This research study aims to explore the current state-of-the-art deep . 9985596 Corpus ID: 255267780; Brain Stroke Prediction Using Deep Learning: A CNN Approach @article{Reddy2022BrainSP, title={Brain Stroke Prediction Using Deep Learning: A CNN Approach}, author={Madhavi K. deep learning for brain stroke detection-a review of recent advance Chin C. used a CNN model in conjunction with texture analysis to detect brain strokes on CT scans. IndexTerms - Brain stroke detection; image preprocessing; convolutional neural network I. The system uses image processing and machine learning techniques to identify and classify stroke regions within the brain, aiming to provide early diagnosis and assist medical professionals brain stroke detection is still in progress. In this paper, our purpose is to diagnose the type of stroke using high-quality images. Brain stroke MRI pictures might be separated into normal and abnormal images In this study, brain stroke disease was detected from CT images by using the five most common used models in the field of image processing, one of the deep learning methods. In this study, we utilized the dataset from the Sub-Acute Ischemic Stroke Lesion Segmentation (SISS) challenge, which is a subset of the larger Ischemic Stroke Lesion The environments in which the two deep learning models were developed and implemented are detailed in Table II. For example, Karthik et al. Seeking medical help right away can help prevent brain damage and other complications. The traditional VGGNet has more layers and the time required to train the network is high. An application of ML and Deep Learning in health care is growing however, some research areas do not catch enough attention for scientific investigation though there is real need of research. Study Type 6 days ago · Brain strokes are a leading reason of affliction & fatality globally, and timely diagnosis is critical for successful treatment. -J. 368–372. Background: Stroke is the second most leading cause of death, the World Health Organization defined stroke as 'rapidly developed clinical signs of focal (or global) disturbance of cerebral function, lasting more than 24 hours or leading to death, which is caused due to blockage or repture of brain The brain is the most complex organ in the human body. ,26 to achieve this objective, an early stroke detection system leveraging CT brain images, alongside a genetic algorithm and a Bidirectional long short-term memory (BiLSTM) model, [1] In a research conducted by Neha Saxena, Deep Singh, Preet Maru, Arvind Choudhary they made an application of ML and Deep Learning by using ML algorithms like Logistic regression, SVM, KNN, Decision Tress and Random Forest to determine and predict the risk of Brain Stroke. The rest of this paper is organized as follows. They experimentally verified an accuracy of more than Nov 21, 2024 · It provides an overview of machine learning and its applications in neuroimaging and brain stroke detection. Jul 1, 2023 · Detection of Ischemic Brain Stroke using Deep Learning S harmila C 1 , 2 , Santhiya S 1 , Poongundran M 1 , Sanjeeth S 1 , and Pr anesh S 1 1 Computer Science and Engineering, Kongu Engi neering Nov 13, 2023 · Dataset and data processing. [5] as a technique for identifying brain stroke using an MRI. In recent years, deep learning-based • The main goal of this research project is to collect stroke datasets and categorise different types of strokes using machine learning and mining methods. INTRODUCTION In most countries, stroke is one of the leading causes of death. -R. INTRODUCTION Stroke is a leading cause of long-term disability worldwide and represents a significant challenge for medical professionals, particularly in terms of early detection and timely intervention [1]. The suggested method uses a Convolutional neural network to classify brain stroke images into normal and pathological categories. May 15, 2024 · When it comes to finding solutions to issues, deep learning models are pretty much everywhere. Augmentation techniques are applied to increase dataset diversity, such as rotating, flipping, or zooming images, enhancing model generalization. The proposed deep learning based brain stroke detection model is presented in this section. Many predictive strategies have been widely used in clinical decision-making, such as forecasting disease occurrence, disease outcome Dec 1, 2023 · Alberta stroke program early CT score calculation using the deep learning-based brain hemisphere comparison algorithm J. The complex and ML approaches to identify brain stroke [8,22,23,24,25,26,27,28,29,30,31]. One of the techniques for early stroke detection is Computerized Tomography (CT) scan. , 30 ( 7 ) ( 2021 ) , Article 105791 , 10. [3] survey studies on brain ischemic stroke detection using deep learning Concerning the context of brain stroke, object detection helps in the quick detection of areas of the brain affected by strokes (clots or hemorrhages), thus facilitating timely interventions. Computer Methods and Programs in Biomedicine . Jul 28, 2020 · Machine learning techniques for brain stroke treatment. Deep Learning Models in Stroke Prediction: Deep learning models, particularly artificial neural networks (ANNs) and convolutional neural networks Jun 26, 2024 · Stroke, a life-threatening medical condition, necessitates immediate intervention for optimal outcomes. The F1 scores, precision and recall attained for the proposed model using deep learning classifiers is compared in Table 2 . Jan 20, 2023 · Prediction of Brain Stroke using Machine Learning Algorithms and Deep Neural Network Techniques January 2023 European Journal of Electrical Engineering and Computer Science 7(1):23-30 Jan 31, 2025 · In early brain stroke detection preprocessing using deep learning, standardizing and normalizing imaging data involves ensuring consistent pixel values and scaling to a standard range. Thus, in this research work, deep learning-based brain stroke detection system is presented using improved VGGNet. An early intervention and prediction could prevent the occurrence of stroke. Second, we aim to evaluate the model’s performance, focusing on accuracy and sensitivity. Healthcare providers can take proactive steps to stop the disease by identifying people who are at high risk of having a brain stroke. III. com Mr. They used pre-processed stroke MRI for classification, trained all layers of LeNet, and distinguished between normal and abnormal patients. The primary objective of this research was to develop a deep learning-based system for stroke detection using CT scan images and a predictive model for assessing stroke risk. The model aims to assist in early detection and intervention of strokes, potentially saving lives and improving patient outcomes Dec 28, 2024 · Early detection using deep learning (DL) and machine learning (ML) models can enhance patient outcomes and mitigate the long-term effects of strokes. Reddy and Karthik Kovuri and J. Segmenting stroke lesions accurately is a challeng-ing task, given that conventional manual techniques are time-consuming and prone to errors. Early identification of strokes using machine learning algorithms can reduce stroke severity & mortality rates. , Wu G. Mohana Sundaram 26 | Page Detection Of Brain Stroke Using Machine Learning Algorithm C) Algorithms i) Decision tree: Decision Tree is a Supervised learning technique that can be used for both classification and Regression problems, but mostly it is preferred for solving Classification problems. KEYWORDS: Stroke detection, Computer vision, Image recognition, Deep learning, CNN 1. , Noguchi S. 2021. [Google Scholar] 12. 105791 Aug 1, 2022 · Meanwhile, Sercan and colleagues focus their work on brain tumour and ischemic and hemorrhagic stroke lesion studies, using deep learning capabilities through the CNN-D-UNet architecture. This study presents a novel approach to meet these critical needs by proposing a real-time stroke detection system based on deep learning (DL) with Fig. Avanija and M. The brain cells die when they are deprived of the oxygen and glucose needed for their survival. pp. In this study, the use of MRI and CT scans to diagnose strokes is compared. The purpose of this paper is to develop an automated early ischemic stroke detection system using CNN deep learning algorithm. Machine Learning (ML) delivers an accurate and quick prediction outcome and it has become a powerful tool in health settings, offering personalized clinical care for stroke patients. Talo M et al (2019) Convolutional neural networks for multi-class brain disease detection using MRI images. 3: Sample CT images a) ischemic stroke b) hemorrhagic stroke c) normal II. This study aims to improve the detection and classification of ischemic brain strokes in clinical settings by introducing a new approach that integrates the stroke precision enhancement better accuracy in brain stroke classification as compared to machine learning classi-fiers, further, the performance of deep learning classifiers is evaluated. proposed a pre-detection and prediction method for machine learning and deep learning-based stroke diseases that measure the electrical activities of thighs and calves with EMG biological signal sensors, which can easily be used to acquire data during daily activities. Deep Singh Bhamra *Corresponding Author: K. An automated early ischemic stroke detection system using CNN deep learning algorithm. Proceedings of the 2017 IEEE 8th International Conference on Awareness Science and Technology (iCAST); November 2017; Taichung, Taiwan. The Dec 31, 2021 · Deep learning techniques with VGG-16 architecture and Random Forest algorithm are implemented for detecting hemorrhagic stroke using brain CT images under segmentation. It is the world’s second prevalent disease and can be fatal if it is not treated on time. It's a medical emergency; therefore getting help as soon as possible is critical. The stroke is tagged, stemmed, and classified in order to accomplish the main goal. The deep learning techniques used in the chapter are described in Part 3. Similar work was explored in [14] , [15] , [16] for building an intelligent system to predict stroke from patient records. We propose a fully automatic method for acute ischemic stroke detection on brain CT scans. Among the several medical imaging modalities used for brain imaging Jan 1, 2023 · In this chapter, deep learning models are employed for stroke classification using brain CT images. Sep 21, 2022 · PDF | On Sep 21, 2022, Madhavi K. Our results imply that the deep learning-based strategy that has been described can be a useful tool for the early detection and prevention of brain stroke. Neural networks are utilized to extract complex information from medical imaging data, making the assessment of stroke indications more accurate and nuanced. Deep Singh Bhamra BrainOK: Brain Stroke Prediction using Machine Learning Mrs. 2020. As a result, early detection is crucial for more effective therapy. Saleem, MA, et al. Neha Saxena Department of Computer Engineering Universal College of Engineering, Vasai, India nehasaxena031@gmail. Keywords—Deep learning; machine learning; stroke; diagnosis; detection; computed tomography I. [14] proposed a method that is both effective and quick for the creation of huge datasets for using in machine learning algorithms to the categorization of brain strokes using microwave imaging devices. We employ a variety of machine learning techniques, including support vector machines (SVM), decision trees, and deep learning models, to efficiently identify and categorize stroke cases from medical imaging data. -L. For the last few decades, machine learning is used to analyze medical dataset. Each year, according to the World Health Organization, 15 million people worldwide experience a stroke. Early detection is crucial for effective treatment. Automatic detection of acute ischemic stroke using non-contrast computed tomography and two-stage deep learning model. However, while doctors are analyzing each brain CT image, time is running Jan 4, 2024 · The main objective of this study is to forecast the possibility of a brain stroke occurring at an early stage using deep learning and machine learning techniques. The organ known as the brain, which is securely protected within the skull and consists of three main parts, namely the cerebrum, cerebellum, and brainstem, is an incredibly complex and intriguing component of the human body. The inability of focus in the brain due to bleeding Nov 29, 2022 · The purpose of this study is to discuss the use of convolutional neural networks, a kind of deep learning technology, in the detection of brain haemorrhage. Based on them, the following sub-objectives are developed: • 1. Early detection using artificial intelligence (AI) can significantly improve patient outcomes[3]. Median filtering is used in the pre-processing of medical pictures. Brain stroke is one of the critical health issues as the after effects provides physical inability and sometimes death. A highly non-linear scale-invariant deep brain stroke detection model, integrating networks like VGG16, network-in-network layer, and spatial pyramid pooling layer (BSD-VNS), is implemented with attributes of the SPP layer that progresses with any gauge of brain stroke measurement. The medical field also greatly benefits from the use of improving deep learning models which save time and produce accurate results. As observed DenseNet-121 classifier provides better the detection of brain stroke. , et al. The Stroke Detection Methods for Stroke Detection Rapid detection of time-sensitive pathologies, such as acute stroke, results in improved clinical outcomes. RELEVANT WORK The majority of strokes are seen as ischemic stroke and hemorrhagic stroke and are shown in Fig. Jul 4, 2024 · Brain stroke, or a cerebrovascular accident, is a devastating medical condition that disrupts the blood supply to the brain, depriving it of oxygen and nutrients. 7,8 For patients with suspected ischemic stroke, early detection with neuro-imaging allows for the faster exclusion of ICH and other stroke mimics, as well as rapid segmentation and prediction Apr 1, 2023 · Download Citation | On Apr 1, 2023, Naga MahaLakshmi Pulaparthi and others published Brain Stroke Detection Using DeepLearning | Find, read and cite all the research you need on ResearchGate Jun 22, 2021 · The stroke prediction module for the elderly using deep learning-based real-time EEG data proposed in this paper consists of two units, as illustrated in Figure 4 . Deep learning algorithms are usually used to detection and diagnostics brain strokes Brain stroke detection and diagnostic algorithms are evaluated using Nov 19, 2023 · As deep learning classifiers gave better accuracy in brain stroke classification as compared to machine learning classifiers, further, the performance of deep learning classifiers is evaluated. cmpb. A stroke or a brain attack is one of the foremost causes of adult humanity and infirmity. This research aims to emphasize the impact of deep learning models in brain stroke detection and lesion segmentation. Comput Med Imaging Graph 78:101673 occurs due to the interruption of blood flow to the brain[1].
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